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Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

RecruitingHealthy volunteers welcome

Slow-wave Sleep Enhancement Using Acoustic Stimulation to Facilitate Performance Recovery During Restricted Sleep After Sleep Deprivation

Who can join

Ages 18 to 39 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Healthy men and non-pregnant, non-lactating women 18 to 39 years of age (inclusive)
* Must demonstrate adequate comprehension of the protocol, by achieving a score of at least 80% correct on a short multiple-choice quiz. Individuals who fail to achieve a passing score on the initial quiz will be given one opportunity to retest after a review of protocol information. Individuals who fail the comprehension assessment for the second time will be disqualified.

Exclusion Criteria:

* You must have learned English as your first language
* You must have a body mass index (BMI) below 30 (this is a mathematical calculation of your height and weight)
* You must not have current or a history of sleeping problems (for example, insomnia or sleep apnea), or symptoms that indicate a potential sleep disorder
* You must get an average of 6-9 hours of sleep per night and maintain a normal sleep/wake schedule
* You must not drink excessive amounts of caffeine, alcohol, or smoke cigarettes regularly
* You must not be on certain medications (determined on a case by case basis)
* You must test negative for illicit drugs
* Women must not be pregnant or nursing
* You must not be participating in another ongoing clinical trial
* You must have a social security number or tax identification number in order to be paid for screening and participation in the study
* You cannot have a history of the following conditions: Cardiovascular disease, a neurologic disorder, pulmonary disease requiring inhaler use, kidney disease or kidney abnormalities, liver disease of liver abnormalities, a history of psychiatric disorder requiring hospitalization or medication within the last two years or for a continuous period of more than 6 months in the last ten years

About the study

The purpose of this study is to determine if brief sounds or tones presented within a restricted period of recovery sleep after a period of sleep deprivation will enhance restorative properties and improve performance during a subsequent period of wakefulness.

What is being tested

Sponsor: Walter Reed Army Institute of Research (WRAIR) · Participants: 44 · Started: Mar 14, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05309473

Locations in the U.S.

MarylandWalter Reed Army Institute of Research, Silver Spring

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.