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Life After Sport: Prior Injury and Sedentary Behavior as Mechanisms of Later Poor Health

RecruitingObservational studyHealthy volunteers welcome

Who can join

Ages 18 to 64 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Please see cohorts for specific inclusion/exclusion criteria

Inclusion Criteria:

* Age 18-25 years OR age 40-64 years
* Current or former collegiate varsity athlete OR non-athlete control

Exclusion Criteria:

* Neurologic (e.g., stroke, Parkinson's) and/or degenerative disease that impairs function
* Pregnancy
* Lower extremity joint replacement (e.g., hip or knee replacement)

About the study

Competitive sport increases risk for musculoskeletal injury (e.g., traumatic knee injury) and may position former athletes for early onset of chronic diseases, chronic pain, poor health-related quality of life, and disability. Quantifying function in former athletes with and without a prior injury and non-athlete controls is critical to understanding long-term health trajectories in athletes and informing potential interventional studies. One modifiable factor that may be associated with long-term health in athletes is physical activity patterns. The purpose of this study is to evaluate strength, function, physical activity, dietary patterns, and cardiometabolic health among current and former competitive athletes and in nonathlete controls to evaluate the impact of prior knee injury and sedentary behavior as two potential determinants of later poor health and reduced function.

Sponsor: Marquette University · Participants: 450 · Started: Apr 18, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05344001

Locations in the U.S.

WisconsinMarquette University, Milwaukee

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.