Home › Attention Deficit Hyperactivity Disorder › NCT05354232

Home-based Transcranial Direct Current Stimulation (tDCS) for Treatment of Attention-deficit/Hyperactivity Disorder (ADHD)

Who can join

Ages 18 to 65 · All sexes

Inclusion Criteria:

1. Male and female outpatients 18-65 years of age
2. A diagnosis of ADD/ADHD or meeting the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) criteria.

Exclusion Criteria:

1. Contraindication to tDCS: history or epilepsy, metallic implants in the head and neck, brain stimulators, vagus nerve stimulators, VP shunt, pacemakers, pregnancy.
2. Active substance dependence (except for tobacco).
3. Pregnant or nursing females.
4. Inability to participate in testing procedures.
5. Premorbid neurological conditions (including neurovascular and neurodegenerative diseases such as traumatic brain injury, stroke, Parkinson's, AD and other dementias) and severe psychiatric disorders (bipolar disorder, schizophrenia).

About the study

The investigators are investigating whether home-based tDCS over the course of four weeks can improve ADHD symptom severity and improve dysexecutive functioning (cognitive control). Further, the investigators are investigating whether there is a dose-dependent response to tDCS.

What is being tested

• 2 mA transcranial direct current stimulation (tDCS) (device)
• 1 mA transcranial direct current stimulation (tDCS) (device)
• Sham transcranial direct current stimulation (tDCS) (device)

Sponsor: Massachusetts General Hospital · Participants: 60 · Started: Jul 1, 2022

Contact the study team

• DNN Inbox · Phone: 6177265348

Official record on ClinicalTrials.gov — NCT05354232

Locations in the U.S.

Conditions

• Attention Deficit Hyperactivity Disorder

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.