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Recording of Intraoperative Spinal Cord Stimulation and Monitoring
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Any patients undergoing brain or spinal cord surgery where spinal neuromonitoring is utilized. Exclusion Criteria: * none
About the study
Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.
What is being tested
- epidural electrical stimulation (device)
Sponsor: University of California, Los Angeles · Participants: 150 · Started: Jan 21, 2011
Contact the study team
- Daniel Lu, MD · Phone: 310/825/4321
Official record on ClinicalTrials.gov — NCT05356286
Locations in the U.S.
| California | University of California, Los Angeles, Los Angeles |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.