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Personalized Perioperative Analgesia Platform (PPAP) for Pediatric Spine Fusion Surgery (sIRB)
Recruiting
Who can join
Ages 10 to 21 · All sexes
Full eligibility criteria
Inclusion Criteria: * Children ages 10 to 21 * ASA physical status 1 to 3 * Undergoing Posterior-Lateral Spinal Fusion * Receives in-patient opioids * Prescribed opioids at discharge Exclusion Criteria: * Serious illness * Preoperative severe pain * Preoperative opioid use or misuse
About the study
The purpose of this collaborative CTSA application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in children undergoing painful surgery.
What is being tested
- Preoperative Genotyping (diagnostic test)
Sponsor: Senthil Sadhasivam · Participants: 300 · Started: Sep 20, 2022
Contact the study team
- Senthilkumar Sadhasivam, MD, MPH · Phone: 4126472994
Official record on ClinicalTrials.gov — NCT05367609
Locations in the U.S.
| California | University of California, San Francisco |
| Florida | Children's Orthopaedic and Scoliosis Surgery Associates, LLP, St. Petersburg (Not yet recruiting) Johns Hopkins All Children's Hospital, St. Petersburg (Not yet recruiting) |
| Indiana | Riley Children's Hospital, Indianapolis |
| Pennsylvania | UPMC Children's Hospital, Pittsburgh |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.