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Assessment of the Ocular Microbiome in Health and Disease
RecruitingObservational studyHealthy volunteers welcome
Who can join
Ages 18 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: We will include subjects who meet all of the following criteria: * 18 years of age or older * Provide informed consent * Cohort A - normal eyes with no ocular disease * Cohort B - primary open angle glaucoma/Ocular hypertension defined as mild glaucoma which is well controlled with no more than one drop of prostaglandin use daily for the past 6 months * Cohort C - non-infectious keratopathy not using any prescription medication (OTC artificial tears are acceptable) * Cohort D - Dry AMD (age related macular degeneration) * Cohort E - Wet AMD * Cohort F - diabetic retinopathy Exclusion Criteria: We will exclude subjects who meet all of the following criteria: * Prior ocular disease either of the anterior or posterior segment * Any medical comorbidities except well controlled DH and HTN * Unable to follow up with study procedures as described
About the study
The objective of this application is to illustrate the core constituents of the ocular surface microbiome, describe factors that promote colonization, and assess the ocular microbiome's role in the health of the anterior segment. We will conduct a prospective, observational cohort study, including a longitudinal analysis of the ocular microbiome in adults.
What is being tested
- Eye swab (other)
Sponsor: Vanderbilt University Medical Center · Participants: 500 · Started: Sep 7, 2023
Contact the study team
- Havin Abdulkadir · Phone: 6159361474
Official record on ClinicalTrials.gov — NCT05414994
Locations in the U.S.
| Tennessee | Vanderbilt University Medical Center, Nashville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.