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Extracellular Vesicles and Particles (EVP) as Biomarkers of Recurrence in Non-Small Cell Lung Cancer

RecruitingObservational study

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* All patients ≥ 18 years of age undergoing consideration of surgical resection, including lobar resections, sublobar resections, and pneumonectomies, for primary lung cancer will be eligible.
* Patients with previously resected disease and/or previous radiation therapy will be considered on a case by case basis.

Exclusion Criteria:

* Patients with active infection or pneumonia which may impact exosome makeup
* Additionally, if at the discretion of the operating surgeon, obtaining bronchial washings would lead to undue morbidity, the patient would be excluded and replaced

About the study

The purpose of this study is to find out if fluid rinsed from peoples' airways (bronchial washing samples) during routine surgery to remove (resect) their non-small cell lung cancer (NSCLC) tumors contains enough vesicles to do testing that may help the researchers learn more about their NSCLC.

Sponsor: Memorial Sloan Kettering Cancer Center · Participants: 200 · Started: Jun 14, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05424029

Locations in the U.S.

New JerseyMemorial Sloan Kettering Basking Ridge (Consent Only), Basking Ridge
Memorial Sloan Kettering Monmouth (Consent Only), Middletown
Memorial Sloan Kettering Bergen (Consent Only), Montvale
New YorkMemorial Sloan Kettering Suffolk - Commack (Consent Only), Commack
Memorial Sloan Kettering Westchester (Consent Only), Harrison
Memorial Sloan Kettering Cancer Center, New York
Memorial Sloan Kettering Nassau (Consent Only), Uniondale

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.