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Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing

RecruitingPhase 4Healthy volunteers welcome

Prospective Randomized Open Label Multicenter Phase IV Clinical Trial to Compare Transforming Powder Dressing (TPD) to Current Standard of Care (SOC) Dressing Therapies in Acute Partial Thickness Burn Wounds

Who can join

Ages 18 to 65 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Hospitalized patients who are receiving burn care; patients may be discharged when clinically stable and continue with outpatient treatment.
* Men and women (women cannot be pregnant or breast feeding) ages 18-65 years old
* Wounds must be partial thickness, involving up to 20% of the total body surface area.
* Burn injury should be less than 72 hours old
* Willing and able to comply with protocol mandated scheduled study visits/clinical evaluations.
* Willing and able to provide written informed consent.

Exclusion Criteria:

* Known allergy to TPD or its components

  * Women who are pregnant, breast feeding, or plan to get pregnant during the study period.
* Infected wounds
* Presence of any full thickness (third degree) burns
* Electrical burns
* Heavily draining burns due to underlying chronic lymphedema or other conditions
* Concurrent clinical condition within the judgement of the clinician, pose a health risk to the patient, delay wound healing, or otherwise influence the outcome of the study.
* History of poor wound healing and/or skin/immune system condition

  * Deemed by clinician not to be suitable
* Unwilling or not able to provide consent or comply with protocol or required visits
* Developmental disability/significant psychological disorder which can impair the subjects ability to provide informed consent, or participate in the study protocol
* Active alcohol or substance abuse

About the study

This study is being performed to assess the effectiveness of Altrazeal(R) Transforming Powder Dressing (TPD) in patients with partial thickness burns compared to the current standard of care (SOC) dressing. Adult men and women 18-65 years old who are hospitalized with an acute (meaning the burn injury occurred less than 72 hours prior to enrollment in the study) partial thickness burn wound, less than 20 percent of total body surface area may be considered. Subjects will be randomized in a 1:1 ratio to either SOC or TPD. Subjects will be followed for up to 28 days after enrollment.

What is being tested

Sponsor: ULURU Inc. · Participants: 60 · Started: May 26, 2022

Contact the study team

Official record on ClinicalTrials.gov — NCT05424354

Locations in the U.S.

CaliforniaUniversity of California-Irvine, Orange
District of ColumbiaMedStar Washington Hospital Center, Washington D.C.
FloridaJackson Memorial Hospital UM/JMH Burn Center, Miami
KentuckyUniversity of Louisville Health, Louisville
New YorkWestchester Medical Center, Valhalla
TexasUniversity of Texas SW (Parkland), Dallas

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.