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Mental Health Crises in Youth With IDDs
Understanding Mental Health Crises in Youth With Intellectual and Developmental Disabilities
Who can join
Ages 7 to 17 · All sexes
Full eligibility criteria
Inclusion Criteria: Child/adolescents admitted to the RCHSD ED with an IDD presenting in a MHC that includes, but is not limited to: * Aggression towards others * Severe agitation * Self-injury * Elopement OR Biological parents of child/adolescent enrolled in this study for the purposes of reflex testing. (Family members are eligible for participation in this study if they presumed genetically related to a participant). Exclusion Criteria: Child/Adolescents participants who do not meet any of the inclusion criteria, or those who: * Already received any prior whole genome sequencing or exome sequencing * Unable to approach the family or patient for enrollment * Unable to obtain informed consent * family members are ineligible for participation in this study if they are known to not be genetically related to the child/adolescent participant and/or if they are a member of a protected research population.
About the study
This study is an unmatched, case-control study of 150 youth (Ages 7-17) with a parent reported Intellectual Developmental Disability (IDD) who present to Rady Children's Hospital Emergency Department with a Mental Health Crisis (MHC). Rady Children's Institute for Genomic Medicine (RCIGM) will collect biological samples (such as blood) of these participants to study their genomes, medical and psychiatric profiles to better understand specific characteristics that may predispose them to MHC's. The 150 youth will be compared to historical, publicly available cohorts of youth with IDD's
What is being tested
- Genomic sequencing and molecular diagnostic results, if any. (genetic)
- EHR-Based Network Model (other)
Sponsor: Rady Pediatric Genomics & Systems Medicine Institute · Participants: 150 · Started: Mar 29, 2023
Contact the study team
- Aaron Besterman, MD · Phone: 858-576-1700
- Corrine Blucher, BS · Phone: 858-576-1700
Official record on ClinicalTrials.gov — NCT05471232
Locations in the U.S.
| California | Rady Children's Hospital San Diego, San Diego |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.