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The Effects of the CF Carrier State on the Kidneys and Pancreas

RecruitingObservational study

Who can join

Ages 18 to 100 · All sexes

Full eligibility criteria
CF Carrier Inclusion Criteria:

* A CF Carrier identified via genetic testing

Control Inclusion Criteria:

* No previous CF carrier test results

Exclusion Criteria:

* CF patient status
* Unable to speak English
* Currently pregnant
* Unable to provide written informed consent
* Prisoner status
* Currently taking any medications for the treatment of diabetes

About the study

The overarching hypothesis is that CF carriers are at increased risk for developing most of the extrapulmonary conditions associated with CF compared to the general population. Specifically, it is hypothesized that this pilot data will detect subclinical evidence of pancreatic and kidney disorders among CF carriers. This will be determined by bringing CF carriers and controls to the CRU for one visit where they will answer survey questions and undergo laboratory testing. Additionally, they will collect urine and stool samples at home that will be sent to outside laboratories for testing.

Sponsor: Philip Polgreen · Participants: 1,250 · Started: Dec 20, 2021

Contact the study team

Official record on ClinicalTrials.gov — NCT05474417

Locations in the U.S.

IowaUniversity of Iowa Hospitals and Clinics, Iowa City

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.