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Accelerated Resolution Therapy for Early Maladaptive Grief

Accelerated Resolution Therapy for Early Maladaptive Grief: A Clinical Trial

Who can join

Ages 60 and older · All sexes · Healthy volunteers welcome

Inclusion Criteria:

* Primary caregiver of immediate family member who has a life expectancy of less than 12 months
* Score of 30 or higher on the PG-12-R, indicating clinically significant pre-loss grief
* Denial of suicidal ideation or intent, with no evidence of psychotic behavior.

Exclusion Criteria:

* Since becoming a family caregiver (FCG), they have engaged in another trauma based psychotherapeutic regimen (EMDR, prolonged exposure therapy, trauma focused cognitive behavioral therapy) that could influence response to accelerated resolution therapy (ART).
* Self-reported or clinically assessed major psychiatric disorder (e.g., bipolar disorder, schizophrenia).
* Score of \> 2 on the adapted CAGE questionnaire indicating alcohol /drug dependence.
* Cognitive impairment (SPMSQ \> 4 errors).

About the study

The purpose study is to test the effects of accelerated resolution therapy (ART) on pre-loss grief and prolonged grief disorder among older adult family caregivers (FCGs). Additionally, to better understand predictors of response to ART, and cognitive processes that occur among grieving individuals following ART.

What is being tested

• Accelerated Resolution Therapy (behavioral)
• Information and Support (other)

Sponsor: Mayo Clinic · Participants: 440 · Started: Nov 17, 2023

Contact the study team

• Katharine E Sheffield, MA, CCRP · Phone: 904-953-3972

Official record on ClinicalTrials.gov — NCT05624879

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.