Home › Spinal Cord Injuries › NCT05670288

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

Who can join

Ages 18 to 85 · All sexes

Inclusion Criteria:

1. 18-85 years of age
2. diagnosis of traumatic SCI at the cervical to lumbar level (C3-L2)
3. classification of A, B, C (motor complete, incomplete).

Exclusion Criteria:

1. Women who are pregnant prior to consent
2. neurological impairment other than SCI
3. self-reported history of Crohn's disease or diverticulitis
4. irritable bowel syndrome
5. gastric blockage/obstruction or swallowing disorder
6. prior GI surgery
7. intrathecal pump
8. concurrent usage of functional electrical stimulation for bowel management (e.g., constipation).
9. able to ambulate

About the study

The Investigators will recruit 35 participants with acute SCI (within 6 weeks of injury) Fasting blood collection and bowel function survey will be conducted 3 times: at baseline \[within 6 weeks of injury\], 6, and 12 months after SCI. Stool will be collected for gut microbiome analysis 3 times.

Sponsor: University of Alabama at Birmingham · Participants: 35 · Started: Oct 15, 2023

Contact the study team

• Jereme Wilroy, PhD · Phone: (205) 934-0355

Official record on ClinicalTrials.gov — NCT05670288

Locations in the U.S.

Conditions

• Spinal Cord Injuries

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.