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Sperm Preparation Prior to Intrauterine Insemination Study
Recruiting
The Sperm Preparation Prior to Intrauterine Insemination Study (PIoUS)
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Patients undergoing intrauterine insemination * Patient assigned female at birth with age \<41 Exclusion Criteria: * Any significant disease or psychiatric disorder that would interfere with the consenting process * Prior intrauterine insemination * Use of frozen donor sperm * Non-English speaker
About the study
This is a randomized controlled trial comparing density gradient centrifugation and microfluidic sperm sorting in patients undergoing intrauterine insemination to evaluate cumulative pregnancy outcomes.
What is being tested
- Zymot Multi sperm separation device (device)
- Density gradient centrifugation (other)
Sponsor: University of California, San Francisco · Participants: 270 · Started: Feb 5, 2023
Contact the study team
- Alisha T Tolani, MD · Phone: 6282867307
Official record on ClinicalTrials.gov — NCT05693220
Locations in the U.S.
| California | UCSF Center for Reproductive Health, San Francisco |
Conditions
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.