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Longitudinal Study for Central Nervous System Vasculitis

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

i. Diagnostic criteria for CNSV

1. The presence of an acquired and otherwise unexplained neurologic deficit
2. The presence of either classic angiographic or histopathologic features of angiitis in the CNS
3. No evidence of systemic vasculitis or any condition that could cause the angiographic or pathologic features

ii. ≥18 years of age

Exclusion Criteria:

i. Unwilling to sign informed consent.

About the study

Primary central nervous system vasculitis (CNSV) is a potentially fatal, single-organ vasculitis that often involves a spectrum of neurologic complications, including strokes, cognitive and speech impairment, visual loss, dementia, and encephalopathy. The purpose of this study is to establish a research cohort to investigate the disease process, treatments, and patient outcomes in CNSV.

Sponsor: University of Pennsylvania · Participants: 40 · Started: Mar 1, 2023

Contact the study team

• Carol McAlear · Phone: 7813214567

Official record on ClinicalTrials.gov — NCT05734404

Locations in the U.S.

Conditions

• Vasculitis

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.