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Optimizing PrEP Uptake and Adherence Among Male Sex Workers
RecruitingHealthy volunteers welcome
Efficacy of a PrEP Uptake & Adherence Intervention Among Male Sex Workers Using a 2-stage Randomization Design
Who can join
Ages 18 and older · Men · Healthy volunteers welcome
Full eligibility criteria
Inclusion * Age: 18 years or older * Assigned male sex at birth * Identifies as male at enrollment * Report having engaged in condomless anal sex with another man in the past 3 months * Report having exchanged sex for money, drugs, items of value, or a place to stay with another man in the past 3 months * Report HIV status as negative or unsure * Not currently on PrEP * Able to understand and speak English or Spanish Exclusion * Unable to provide informed consent due to severe mental or physical illness, cognitive impairment, or substance intoxication at the time of interview (will use an adapted version of the Evaluation to Sign Consent Form65 to assess capacity) * Discovery of active suicidal ideation or major mental illness (e.g. untreated psychosis or mania) at the time of interview (these patients will be referred immediately for treatment) * Laboratory or clinical findings that would preclude PrEP initiation (e.g. Chronic Hepatitis B Virus infection, decreased creatinine clearance) * Participated in the pilot RCT and initiated PrEP during study participation
About the study
"PrEPare for Work" is a randomized controlled trial (RCT) whose goal is to test the efficacy of a behavioral intervention (Short Title: PrEPare for Work) in improving PrEP uptake, adherence, and persistence among male sex workers (MSW)
What is being tested
- Stage 1 Strength Based Case Management (SBCM) Condition (behavioral)
- Stage 2 PrEPare for Work Intervention Condition (behavioral)
Sponsor: Brown University · Participants: 500 · Started: Nov 3, 2022
Contact the study team
- Katie Biello, PhD · Phone: 401-863-3082
- Matthew Mimiaga, ScD MPH · Phone: 617 901 9276
Official record on ClinicalTrials.gov — NCT05736614
Locations in the U.S.
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.