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PROton Therapy for Post Surgical Treatment of GYNecologic Cancer
Adjuvant Proton Whole Pelvis Radiation Therapy for Treatment of Post-Surgical Gynecologic Cancers
Who can join
Ages 18 and older · Women
Full eligibility criteria
Inclusion Criteria: * Histologically confirmed cervical or endometrial cancer * Indication for adjuvant whole pelvic radiation therapy, with or without systemic therapy * Age of 18 years or older * Written informed consent * ECOG of 0-2 within 3 months of enrolling Exclusion Criteria: * Prior course of pelvic radiation * Metastatic disease outside of the pelvis * Active inflammatory bowel disease * Incapacity to provide informed consent
About the study
This is a single institution, multi-center, Phase II, single-arm study, using Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) in the post-surgical, adjuvant setting for definitive treatment of gynecologic cancers. The purpose of this study is to estimate rate of acute clinician-reported gastrointestinal (GI) toxicity using WP PBS PRT in the definitive treatment of gynecologic cancers in the post-surgical, adjuvant setting.
What is being tested
- Whole Pelvis (WP) Pencil Beam Scanning Proton Radiation (PBS PRT) (radiation)
Sponsor: Abramson Cancer Center at Penn Medicine · Participants: 25 · Started: Nov 6, 2023
Contact the study team
- Project Manager · Phone: 215-662-3790
Official record on ClinicalTrials.gov — NCT05758688
Locations in the U.S.
| New Jersey | Virtua Health, Voorhees Township |
| Pennsylvania | Lancaster General Health - Ann B. Barshinger Cancer Institute, Lancaster University of Pennsylvania, Philadelphia |
Conditions
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.