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Interoceptive Exposure for Adolescents With Low Weight Eating Disorders
A Confirmatory Efficacy Study of Interoceptive Exposure for Adolescents With Low Weight Eating Disorders
Who can join
Ages 12 to 18 · All sexes
Full eligibility criteria
Inclusion Criteria: * Aged 12-18 * Speak English * Permission from pediatrician or equivalent to receive outpatient care * Clinically significant restriction of food intake by EDA-5 or evidence of persistent food avoidance from patient or guardians * Evidence of the inability to maintain greater than minimally low body weight based on BMI for age percentiles and growth trajectories Exclusion Criteria: * Comorbid psychotic or bipolar disorder * Active suicidal ideation * Current substance dependence * Psychiatric medication initiated or dosage changes \<2 weeks from baseline * Major medical illness (e.g., diabetes mellitus, Crohn's disease, etc.)
About the study
This project includes a parallel group randomized controlled trial comparing two psychological treatments: 1) Exposure-based Family Therapy (IE) vs. 2) Family Based Therapy (FBT) for low weight eating disorders with 12 month follow-up. Primary outcomes are expected body weight and clinical impairment. Three mechanisms of change (Autonomous Eating, Non-Judgmental Body Awareness, and Extinction Learning) will be examined in a process mediation models of change.
What is being tested
- Interoceptive Exposure Treatment (IE) (behavioral)
- Family-Based Treatment (FBT) (behavioral)
Sponsor: Icahn School of Medicine at Mount Sinai · Participants: 120 · Started: Mar 14, 2023
Contact the study team
- Thomas Hildebrandt, Psy.D. · Phone: (212) 659-8673
- Jessica Bibeau, MA · Phone: 212-659-8673
Official record on ClinicalTrials.gov — NCT05763849
Locations in the U.S.
| New York | Department of Psychiatry, Eating and Weight Disorders Program, New York |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.