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Hyperpolarized 129Xe MRI Lung Health Cohort
Hyperpolarized 129Xe MRI to Identify Structural Determinants of Low Lung Function and Respiratory Symptoms in Young Adults From the Lung Health Cohort
Who can join
Ages 25 to 35 · All sexes
Full eligibility criteria
Inclusion Criteria: * Is enrolled in the American Lung Association Lung Health Cohort Study. * Has completed CT imaging for the LHC study within 2 years of the scheduled Xe-MRI date. Exclusion Criteria: * Pacemaker, internal defibrillator or other implanted electronic devices or any standard MRI contraindications (e.g., claustrophobia, \> 140 cm shoulder circumference, dependent on weight distribution). * Is pregnant or breastfeeding * Oxygen saturation (SpO2) \<88% on room air or with supplemental oxygen.
About the study
A subset of young adults participating in the American Lung Association (ALA) Lung Health Cohort (LHC) will be imaged using Hyperpolarized 129Xe MRI to assess lung structure and function. Images will be used to improve the understanding of lung health and early lung abnormalities that may lead to chronic lung disease.
What is being tested
- Hyperpolarized Xe129 (drug)
Sponsor: University of Kansas Medical Center · Participants: 260 · Started: Nov 30, 2023
Contact the study team
- Cristal Monge · Phone: 913-945-9399
Official record on ClinicalTrials.gov — NCT05766384
Locations in the U.S.
| Illinois | University of Illinois-Chicago, Chicago (Not yet recruiting) |
| Iowa | University of Iowa, Iowa City |
| Kansas | University of Kansas Medical Center, Kansas City |
| North Carolina | Duke University, Durham |
| Texas | Baylor College of Medicine, Houston (Not yet recruiting) MD Anderson Cancer Center, Houston (Not yet recruiting) |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.