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Opioid-Sparing Effects of Nurse-Delivered Hypnosis During Breast Cancer Surgery

RecruitingPhase 2/3

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

1. Men and Women;
2. Age 18 or older;
3. Scheduled for a unilateral, breast surgical procedure, ± SLND
4. Able to read, write and speak English or Spanish
5. Able to sign a written informed consent and be willing to follow protocol requirements

Exclusion Criteria:

1. Extreme mobility issues that preclude participating in the study
2. Major thought disorders such as schizophrenia or uncontrolled bipolar disorder or PTSD
3. History of chronic opioid use
4. Current pain 2 or above on 0-10 scale
5. Co-mobilities such as uncontrollable diabetes or hypertension
6. Plastic surgery involvement for oncoplastic reconstruction
7. Surgery is likely greater than 3 hours
8. Patients with hearing loss that could preclude HS facilitation
9. Known allergy to propofol or other medications used during surgery

About the study

To hypnosedation alone given before and during surgery on reducing opioid use after surgery compared to standard general anesthesia given alone or with hypnosedation.

What is being tested

Sponsor: M.D. Anderson Cancer Center · Participants: 225 · Started: Oct 12, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05766891

Locations in the U.S.

TexasM D Anderson Cancer Center, Houston

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.