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Effects of Breathing and Attention Training (BAT) on Pain Modulation
Effects of Breathing and Attention Training (BAT) on Pain Modulation in Healthy Individuals and Patients With Chronic Musculoskeletal Pain
Who can join
Ages 18 to 70 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Individuals diagnosed with fibromyalgia will have pain of duration \> 6 months and meeting the 1990 Research Diagnostic Criteria for FM (ACR) * Healthy, pain-free age matched controls without chronic pain Exclusion Criteria: * Personal or family history of photosensitive epilepsy * Prior history of cancer or diabetes * Patients must be willing to discontinue their analgesics, hypnotics, anxiolytics, or anti-depressants during the study period for at least 5 half-lives.
About the study
The hypersensitivity of fibromyalgia is associated with abnormal pain modulation within the CNS, but not with peripheral or central sensitization. Many brain areas that contribute to modulation of pain are known, but their testing is complex and expensive. Quantitative sensory testing is easier to perform and repeatable. Therefore, it will be used to evaluate the effects of Breathing Attention Training (BAT) on the hypersensitivity of FM participants. BAT is a form of mindfulness meditation shown to decrease FM symptoms and possibly pain sensitivity. We hypothesize that pain modulation of chronic pain patients is improved by BAT.
What is being tested
- Breathing and Attention Training (BAT) (behavioral)
- Breathing Control (behavioral)
Sponsor: University of Florida · Participants: 40 · Started: Apr 3, 2023
Contact the study team
- Melyssa Godfrey · Phone: 352-265-8901
Official record on ClinicalTrials.gov — NCT05773482
Locations in the U.S.
| Florida | University of Florida, Gainesville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.