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Feasibility of an In-home Standing and Walking Intervention for Infants With and at High Risk of Cerebral Palsy

Recruiting

Who can join

5 Months – 2 Years · All sexes

Full eligibility criteria
Inclusion Criteria:

* Infants with or at high risk of cerebral palsy (CP) who either:

  * have been diagnosed with CP by a medical professional, or
  * are at high risk of CP defined as having both:

    * clinical brain imaging indicating CP, such as (i) white matter injury (cystic periventricular leukomalacia or periventricular hemorrhagic infarctions), (ii) hypoxic-ischemic encephalopathy, or (iii) neonatal stroke, and
    * a score less than 63 or more than 5 asymmetries on the Hammersmith Infant Neurological Examination (HINE).

Exclusion Criteria:

* prenatal substance abuse,
* congenital malformations,
* drug-resistant epilepsy,
* visual impairment that hinders the infant from seeing toys,
* hearing impairment that hinders the infant from responding to sound,
* living in a location inaccessible by study personnel for in-home data collections,
* participant over 50 lbs in weight.

About the study

The purpose of this study is to evaluate the feasibility and begin to evaluate the effect of an intensive in-home standing and walking intervention for infants with or at high risk of cerebral palsy.

What is being tested

Sponsor: University of Southern California · Participants: 8 · Started: Mar 26, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05781438

Locations in the U.S.

CaliforniaUniversity of Southern California, Los Angeles

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.