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Ovarian PRP for Diminished Ovarian Reserve

RecruitingHealthy volunteers welcome

Ovarian Platelet-Rich Plasma Injections for Diminished Ovarian Reserve Patients: A Double-Blinded Placebo-Control Trial

Who can join

Ages 35 to 42 · Women · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Clinical diagnosis of diminished ovarian reserve
* Clinical diagnosis of poor ovarian response
* Women age 35-42

Exclusion Criteria:

* Clinical diagnosis of premature ovarian failure
* Clinical diagnosis of menopause.
* Under 35 years of age
* Over 42 years of age

About the study

This prospective double-blinded randomized placebo control study aims to determine if In Vitro Fertilization (IVF) outcomes are improved by ovarian platelet-rich plasma injections (oPRP) for women diagnosed with diminished ovarian reserve (DOR). Women with DOR notoriously have the lowest chance of pregnancy and live birth compared to age-matched peers with a normal or robust ovarian reserve.

What is being tested

Sponsor: Generation Next Fertility · Participants: 230 · Started: Oct 7, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05790655

Locations in the U.S.

New YorkGeneration Next Fertility, New York

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.