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Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure
RecruitingHealthy volunteers welcome
Omega-3 Fatty Acid Modulation of Brown Adipose Tissue for Arctic Resilience
Who can join
Ages 18 to 40 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Male and female, between the ages of 18 to 40 years. * Body Mass Index (BMI) of 18.5 to 24.9 kg/m2 * Considered "moderately to highly active" by the International Physical Activity Questionnaire (IPAQ) and the Physical Activity Readiness Questionnaire (PAR-Q+) Exclusion Criteria: * History of smoking or recreational smoking, hyperlipidemia, hypertension/cardiovascular disease, diabetes, renal disease, neurological disease, metabolic disease, and bleeding disorders or delayed clotting time. * Taking SSRI's (antidepressants and anxiety medication), ADD/ADHD medication, and chronically consume pain medication (Aleve, Tylenol, CBD, etc). * Have or have had chronic disorders of the rectum (e.g., cancer, surgery, active hemorrhoids, etc.) or who currently have related acute conditions (diarrhea, constipation, etc.). * Have or have had a diagnosis of disorders related to immune suppression and/or autoimmune disease. * Are pregnant or planning on being pregnant. * Resting blood pressure of \> 130mmHg systolic or 90 mmHg diastolic. * Resting Pulse rate of \> 100 bpm. * History of regularly consuming fish oil supplements and/or regularly eating more than one fish meal per week. * Consuming more than one fish meal per week during the study.
About the study
This clinical trial will assess the whether fish oil supplementation can modulate brown fat activation, shivering, thermal comfort and skin blood flow during cold exposure.
What is being tested
- Fish Oil (dietary supplement)
- Placebo (dietary supplement)
Sponsor: Indiana University · Participants: 30 · Started: Jun 12, 2023
Contact the study team
- Timothy D Mickleborough, PhD · Phone: 812-855-0753
Official record on ClinicalTrials.gov — NCT05822141
Locations in the U.S.
| Indiana | Human Perfromance Lab, Indiana University, Bloomington |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.