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Trifecta-Lung cfDNA-MMDx Study

RecruitingObservational study

Trifecta-Lung cfDNA-MMDx Study: Comparing the Dd-cfDNA Test to MMDx Microarray Test and Central HLA Antibody Test

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

Adult, Older adult

Exclusion Criteria:

Patients will be excluded from the study if they decline participation Are unable to give informed consent. Recipients of multiple organs, cancer patients and pregnant women

About the study

Demonstrate the relationship between dd-cfDNA levels and HLA antibodies in blood transplant recipient and Demonstrate the Molecular Microscope® (MMDx) Diagnostic System results in indication and protocol biopsies from lung transplants.

Sponsor: University of Alberta · Participants: 600 · Started: Nov 1, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05837663

Locations in the U.S.

ArizonaSt. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT, Phoenix
FloridaDivision of Pulmonary, Critical Care and Sleep Medicine, University of Florida, College of Medicine, Gainesville
Mayo Clinic Florida, 4500 San Pablo Rd, Jacksonville
USF Health, Morsani College of Medicine, 12901 Bruce B. Downs Blvd. MDC40, Tampa (Not yet recruiting)
IndianaIndiana University Methodist Hospital 1812 N. Capitol Ave Suite W131L, Indianapolis
MarylandJohns Hopkins Interventional Pulmonology, Sheikh Zayed Tower, Room 7125L, 1800 Orleans Street, Baltimore
New YorkDivision of Pulmonary, Allergy & Critical Care Medicine Columbia University Irving Medical Center, New York
OhioThe Ohio State University Wexner Medical Center, 410 W 10th Ave, Columbus
TexasBAYLOR SCOTT & WHITE RESEARCH INSTITUTE , 3409 Worth Street, Dallas
UT Southwestern Medical Center, 5939 Harry Hines Blvd., Dallas
Houston Methodist Lung Transplant Center, 6550 Fannin St., SM1001, Houston
UT Health San Antonio 7703 Floyd Curl Drive, MSC: 7858, San Antonio

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.