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Treatment of Orthostatic Hypotension in SCI
RecruitingPhase 4
Treatment of Orthostatic Hypotension in Individuals With Spinal Cord Injury
Who can join
Ages 18 to 60 · All sexes
Full eligibility criteria
Inclusion Criteria: * traumatic spinal cord injury * at least 12 months post injury * injury level of C1-T6 * AIS A, B or C * non-ambulatory * non-ventilator Exclusion Criteria: * Active psychiatric disorder * Stroke or cerebrovascular disease * Alzheimer's Disease or dementia * Unmanaged cardiac arrhythmias * Concurrent systemic, hepatic, or renal disease * Suspected or diagnosed malignancy * Neurological disease other than SCI * Self-reported history of three or more symptomatic episodes of AD per day
About the study
The purpose of this study is to identify the effects of non-pharmacological and pharmacological anti-hypotensive treatment interventions on orthostatic hemodynamic responses, symptoms of autonomic dysreflexia and orthostatic hypotension, and levels of fatigue and comfort in hypotensive individuals with SCI.
What is being tested
- Midodrine Hydrochloride (drug)
Sponsor: James J. Peters Veterans Affairs Medical Center · Participants: 25 · Started: Jul 1, 2023
Contact the study team
- Matt T Maher, MS · Phone: 9733243588
- Dylan C Arnero, MA · Phone: 718-584-9000
Official record on ClinicalTrials.gov — NCT05839652
Locations in the U.S.
| New Jersey | Kessler Foundation, West Orange |
| New York | James J Peters VA Medical Center, The Bronx |
Conditions
From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.