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Mindfulness, Optimism, and Resilience for Perinatal Health and Equity Study

Who can join

Ages 18 and older · Women

Inclusion Criteria:

* Able to provide informed consent
* English speaking
* Nulliparous (no prior delivery at or greater than 20w0d gestation)
* Pregnant with singleton fetus
* \<20w0d gestation
* Low dispositional optimism (score \</= 14 on the Revised Life Orientation Test)
* Owns a smart phone

Exclusion Criteria:

* Plan to deliver at another institution
* Ongoing (≥1/week) mind-body practice including mindfulness training, meditation or yoga
* Pre-gestational hypertensive disorder
* Pre-gestational diabetes mellitus

About the study

Dispositional optimism (the general assumption that more good things than bad will occur across various life domains) has been tied to improved somatic and mental health outcomes. Dispositional optimism is malleable, although prior interventions have been time and resource intensive and thus are not well-tailored to the peripartum period. The purpose of this pilot study is to evaluate the feasibility and acceptability of a pregnancy-oriented mindfulness phone application (Expectful) versus standard care among first-time mothers with low dispositional optimism in early pregnancy. Other aims include evaluating the impact of Expectful use on dispositional optimism, adverse pregnancy outcomes (cesarean delivery, hypertensive disorders of pregnancy, and gestational diabetes) and postpartum post-traumatic stress symptoms.

What is being tested

• Digital Mindfulness Training (behavioral)

Sponsor: Nina Ayala · Participants: 100 · Started: Feb 20, 2024

Contact the study team

• Nina K Ayala, MD, MSCR · Phone: 401-274-1100
• Emily S Miller, MD, MPH · Phone: 401-274-1100

Official record on ClinicalTrials.gov — NCT05840900

Locations in the U.S.

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.