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Breathing Training and Exercise Capacity in Non-CFB
Recruiting
Home-based, Digitally Delivered Breathing Training in People With Non-cystic Fibrosis Bronchiectasis: A Randomized Control Trial
Who can join
Ages 21 to 80 · All sexes
Full eligibility criteria
Inclusion Criteria: * Mayo Clinic patient with confirmed diagnosis of Non-Cystic Fibrosis Bronchiectasis (non-CFB): Non-CFB as confirmed by clinical history, including cough, shortness of breath, exertional dyspnea, pulmonary function tests, and high-resolution computed tomography. Patients will be considered clinically stable if there is no evidence of an exacerbation or change(s) in medical therapy in the previous three weeks. * Able and willing to provide informed consent to participate in the study. Exclusion Criteria: * Presence of significant coexisting disease, neurological conditions, and/or orthopedic complications that affect ability to undertake exercise. * Presence of advanced heart failure. * Current use of antibiotics. * Acute exacerbation(s) within 3-weeks prior to study commencement. * Participation within a pulmonary rehabilitation program within 6-months prior to study commencement.
About the study
The purpose of this research is to investigate whether a home-based and health coach supported specific breathing and respiratory muscle training program improves the ability to exercise, the function of the lungs and breathing muscles, and general clinical status in people with non-cystic fibrosis bronchiectasis (non-CFB).
What is being tested
- LungTrainers (device)
- LungTrainers Pulmonary Rehabilitation regime (behavioral)
Sponsor: Mayo Clinic · Participants: 50 · Started: Jan 15, 2024
Contact the study team
Official record on ClinicalTrials.gov — NCT05860803
Locations in the U.S.
| Florida | Mayo Clinic Florida, Jacksonville |
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.