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Beetroot Juice and Sleep
RecruitingHealthy volunteers welcome
Effects of Nocturnal Inorganic Nitrate Supplementation on Physiological Function
Who can join
Ages 18 to 80 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * 18-35 or 65-80 years of age Exclusion Criteria: * Coronary artery disease * Heart failure * Pregnancy * Diabetes * Sleep disorders * Shift workers * Individuals who typically go to sleep after midnight * Individuals who traveled across ≥2 time zones within one week of study visits * Individuals with a history frequent kidney stones * BMI ≥35.0kg/m2 * Use of nicotine-containing products within the two years preceding study visits * Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with the nitrate-nitrite-nitric oxide pathway or outcome measures
About the study
The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.
What is being tested
- Active Beetroot Juice Supplement (aBRJ) (dietary supplement)
- Placebo Beetroot Juice Supplement (pBRJ) (dietary supplement)
Sponsor: Mayo Clinic · Participants: 60 · Started: Sep 28, 2023
Contact the study team
- Joshua Bock, PhD · Phone: (507) 422-0768
- Virend Somers, MD, PhD · Phone: (507) 255-1144
Official record on ClinicalTrials.gov — NCT05864521
Locations in the U.S.
| Minnesota | Mayo Clinic in Rochester, Rochester |
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.