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Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning

Advancing Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning - a Prospective Study

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* Must have a radiological diagnosis of a lesion in the brain with characteristics consistent with glioblastoma multiforme.
* Must be planning to undergo a pre-operative MRI.
* Must be at least 18 years old.
* Must be able to understand and willing to sign an IRB approved written informed consent document.

Exclusion Criteria:

* Contraindication to MRI.
* Inability to have clinical follow-up (e.g., patient is out of town and will do follow-up elsewhere).

About the study

This study is investigating the use of a computer algorithm to analyze scans of the brain before surgery to predict how a person's tumor will respond to treatment.

What is being tested

• Support Vector Machine (device)

Sponsor: Washington University School of Medicine · Participants: 100 · Started: Dec 6, 2023

Contact the study team

• Dimitrios Mathios, M.D. · Phone: 314-747-6146

Official record on ClinicalTrials.gov — NCT05864976

Locations in the U.S.

Conditions

• Glioblastoma

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.