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Perceptual Consequences of Cochlear Implant Electrode-neuron Interfaces

Development and Assessment of Listener-tailored Programming for Cochlear Implant Listeners

Who can join

3 Months · All sexes · Healthy volunteers welcome

Inclusion Criteria:

Research Subjects with a Cochlear Implant ADULTS Inclusion Criteria

* Adult at least 18 years old
* Native speakers of American English
* Wears a cochlear implant manufactured by Advanced Bionics (Clarion Hi-Focus I or newer), Cochlear, or MED-EL

CHILDREN Inclusion Criteria

* Children at least 3 months old
* Native speakers of American English
* Wears a cochlear implant manufactured by Advanced Bionics (Clarion Hi-Focus I or newer), Cochlear, or MED-EL

  * For both children and adults with a cochlear implant, some study criteria might pertain to a subset of subjects, such as a specific age at which the subjects developed a hearing loss, or was implanted.

Exclusion Criteria:

Exclusion for all Cochlear Implant Subjects:

* Inability to provide informed consent
* Does not meet the inclusion criteria for a specific study protocol, such as age of onset of hearing loss, age of cochlear implantation, duration of deafness, number of active electrodes in the cochlear implant device
* Unable to carry out the study protocol or tasks required in the study

Exclusion for all Normal Hearing Subjects:

* Inability to provide informed consent
* Hearing loss, or significant history of hearing related issues
* Unable to carry out the study protocol or tasks required in the study

About the study

Despite the success of cochlear implants, devices surgically placed in the inner ears of patients with severe hearing loss, there remains substantial variability in the overall speech perception outcomes for the children and adults who receive them. The main goals of this project are: i) to improve our understanding of how cochlear implants affect the developing auditory system, ii) apply that knowledge to test new methods for programming children and adults, and iii) to study how long it takes listeners to adapt to new cochlear implant programs over the short- and long-term. The results will improve our understanding of how the deafened auditory system develops with cochlear implant stimulation and advance clinical practice to improve hearing outcomes in cochlear implant listeners.

What is being tested

• Experimental Speech Processing Strategy (other)

Sponsor: Massachusetts Eye and Ear Infirmary · Participants: 200 · Started: Sep 16, 2022

Contact the study team

• Julie Arenberg · Phone: 617-807-7904

Official record on ClinicalTrials.gov — NCT05867173

Locations in the U.S.

Conditions

• Hearing Disorders and Deafness

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.