Home › Metabolic Syndrome › NCT05880758
Impact of Yo-Yo Sleep on Cardiometabolic Health
Who can join
Ages 18 to 49 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Aged 18 to 49 years * BMI 20-29.9 kg/m2 * Habitually sleeping 7-9 hours/night without sleep aids or naps Exclusion Criteria: * Sleep disorders * Psychiatric disorders (including eating disorders) and seasonal affective disorder * Pregnancy (current/prior year) * Breastfeeding * Smokers (Any cigarette smoking or ex-smokers \<3years) * Diabetes * Elevated blood pressure, taking beta-blockers * Individuals taking anti-coagulants or anti-platelets * Recent weight change or participation in a weight loss program or have ever had bariatric surgery or other weight loss or gastrointestinal procedure. * Travel across time zones; shift work (non-traditional hours)
About the study
The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).
What is being tested
- Intermittent Short Sleep (ISS) (behavioral)
- Social Jetlag (SJL) (behavioral)
- Sustained Adequate Sleep (SAS) (behavioral)
Sponsor: Columbia University · Participants: 72 · Started: Sep 22, 2023
Contact the study team
- Marie-Pierre St-Onge, PhD · Phone: 212-305-9549
- Greiby Mercedes · Phone: 646-761-3455
Official record on ClinicalTrials.gov — NCT05880758
Locations in the U.S.
| New York | Columbia University Irving Medical Center, New York |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.