Home › Insulin Resistance › NCT05912348
The Effects of an Obesogenic Lifestyle in Recreationally Active, Young Adults
Who can join
Ages 18 to 30 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * 18-30 years of age * Recreationally active completing 75-150 minutes of moderate-to-vigorous intensity exercise (\>2 days/week). * Fair cardiorespiratory fitness levels (Men: VO2\>38.4 ml/kg/min; Women: VO2\>32.6 ml/kg/min). Exclusion Criteria: * Hypertension (resting or diagnosed) * Impaired fasting blood glucose (\>100mg/dL) * Diagnosed cardiovascular disease * Diagnosed diabetes * Diagnosed cancer * Diagnosed chronic kidney disease * Diagnosed musculoskeletal disorders that prevents the individual from exercising on a bike.
About the study
This clinical trial aims to learn about the alterations in insulin resistance and metabolic flexibility following a transition to an obesogenic lifestyle in fit young men and women. The main questions it aims to answer are:
1. Does adding excess carbohydrates when transitioning to a sedentary lifestyle promote insulin resistance and impaired 24hr glucose regulation in healthy men and women? 2. Does adding excess carbohydrates when transitioning to a sedentary lifestyle lower the body's ability to break down fats and carbohydrates in healthy men and women? 3. Does the added physical activity blunt shifts in carbohydrate and fat oxidation in healthy men and women?
What is being tested
- Low Physical Activity and Added Carbohydrate Group (behavioral)
- Low physical Activity Control (behavioral)
- High Physical Activity and Added Carbohydrate Group (behavioral)
Sponsor: University of New Hampshire · Participants: 45 · Started: Feb 8, 2023
Contact the study team
- Michael Brian, PhD · Phone: 603-714-8899
Official record on ClinicalTrials.gov — NCT05912348
Locations in the U.S.
| New Hampshire | University of New Hampshire Cardiometabolic Research Laboratory, Durham |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.