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Effects of rTMS on Food Choice in Anorexia Nervosa

Recruiting

Deciphering the Neural Mechanisms of Restrictive Eating in Anorexia Nervosa Using Repetitive Transcranial Magnetic Stimulation

Who can join

Ages 18 to 35 · Women

Full eligibility criteria
Inclusion Criteria:

* DSM-5 Diagnosis of Anorexia Nervosa
* Age 18-35 years
* Female
* Right-handed
* Body Mass Index (BMI) ≥ 16.0
* Voluntarily admitted to inpatient eating disorders unit at NYSPI
* Competent to provide informed consent
* English-speaking
* Medically stable

Exclusion Criteria:

* High risk of suicide
* Current substance use disorder or other co- morbid psychiatric condition requiring specialized treatment (e.g., psychosis)
* Diagnosis of major medical or neurological problem or taking medication that significantly increases risk for seizure or affects interpretation of findings (e.g., unstable hypertension, seizure disorder)
* Food restrictions (e.g., allergies) which impact greater than 30% of food choice task's choice options
* Indwelling ferromagnetic metallic object (e.g., pacemaker, pump), non- removable metal jewelry, medicinal patch or recent metallic ink tattoo
* History of seizure
* Diagnosis of epilepsy, stroke, multiple sclerosis, traumatic brain injury, Alzheimer's and other neurodegenerative diseases, meningoencephalitis or intracerebral abscess, or parenchymal or leptomeningeal cancers
* Prior exposure to TMS
* Pregnancy
* Currently breast-feeding
* Significant claustrophobia
* Implanted devices or stimulators
* Hearing loss (e.g., currently undergoing treatment with ototoxic medications or those with cochlear implants)

About the study

This study will examine the impact of high-frequency repetitive transcranial magnetic stimulation on food choice behavior and related neural activity.

What is being tested

Sponsor: New York State Psychiatric Institute · Participants: 72 · Started: Apr 24, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05918835

Locations in the U.S.

New YorkNew York State Psychiatric Institute, New York

Conditions

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.