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Observational Study for Patients at Risk for Chronic Graft-Versus-Host Disease

RecruitingObservational study

A Prospective, Observational Cohort Study of Participants at Risk for Chronic Graft-Versus-Host Disease in the United States (THRIVE)

Who can join

Ages 18 and older · All sexes

Full eligibility criteria
Inclusion Criteria:

* Age ≥ 18 years inclusive at the time of signing the ICF
* Allogeneic SCT 90 to 180 days prior to enrollment
* Able to comprehend and willing to provide informed consent
* Willing and able to complete participant-assessment questionnaires either alone or with minimal assistance from a caregiver and/or trained site personnel

Exclusion Criteria:

* There are no exclusion criteria for this study

About the study

The purpose of this prospective observational study is to collect data from participants who have recently had an allogenic Stem Cell Transplant(alloSCT) and are at risk of Chronic Graft Versus Host Disease(cGVHD)

What is being tested

Sponsor: Incyte Corporation · Participants: 1,500 · Started: Aug 1, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05919511

Locations in the U.S.

AlabamaUniversity of Alabama Birmingham, Birmingham
ArizonaMayo Clinic Arizona, Phoenix
CaliforniaCity of Hope, Duarte
USC Norris Comprehensive Cancer Center, Los Angeles
ColoradoUniversity of Colorado, Aurora
FloridaMayo Clinic Jacksonville, Jacksonville
AdventHealth Orlando, Orlando
Moffit Cancer Center, Orlando
GeorgiaEmory University, Atlanta
Georgia Cancer Center, Augusta
IllinoisNorthwestern University, Chicago
Rush University Medical Group, Chicago
The University of Chicago, Chicago
Loyola University Medical Center, Maywood
KansasThe University of Kansas Clinical Research Center, Fairway
MarylandUniversity of Maryland Medical Center, Baltimore
MassachusettsMassachusetts Cancer Research Center, Boston
MichiganCorewell Health, Grand Rapids
MinnesotaMayo Clinic Rochester, Rochester
New JerseyRutgers Cancer Institute of New Jersey, New Brunswick
New YorkMemorial Sloan Kettering Cancer Center, New York
North CarolinaUniversity of North Carolina at Chapel Hill, Chapel Hill
Levine Cancer Institute, Charlotte
OhioThe Ohio State University, Columbus
OregonOregon Health Sciences University, Portland
PennsylvaniaGeisinger Health Systems, Danville
TennesseeVanderbilt University Medical Center, Nashville
TexasTexas Oncology-Baylor Charles A. Sammons Cancer Center, Dallas
UtahUniversity of Utah, Huntsman Cancer Institute, Salt Lake City
WashingtonFred Hutchinson Cancer Research Center, Seattle
WisconsinMedical College of Wisconsin, Milwaukee

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.