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Nasal Obstruction and Olfactory Losses
Novel Mechanisms and Therapeutic Approaches for Nasal Obstruction and Olfactory Losses
Who can join
Ages 18 to 70 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: 1. Smell Loss complaints 2. Nasal Obstruction Exclusion Criteria: 1. Congenital olfactory losses 2. Nasal polyps, blocking the olfactory cleft 3. Significant atrophy 4. Cystic fibrosis 5. Wegeners or any other connective tissue disorder 6. Head trauma
About the study
About 13% of US adults, some 30 million people, suffer from nasal sinus disease. Although nasal obstruction and smell loss are two of the major symptoms of the disease that are crucial to disease management, currently there is a lack of clinical tools to effectively evaluate the mechanisms contributing to these symptoms. The proposed study aims to develop novel clinical tools to better evaluate and relieve patients' nasal obstructive symptoms and to enable patients and clinicians to make more informed, personalized decisions regarding treatment strategy.
What is being tested
- Nasal Plug (other)
Sponsor: Ohio State University · Participants: 330 · Started: Jan 25, 2023
Contact the study team
- Veronica Formanek, BS · Phone: 630-501-8168
- Beth Miles-Markley, MS · Phone: 614-366-9244
Official record on ClinicalTrials.gov — NCT05920330
Locations in the U.S.
| Ohio | Eye and Ear Institute, 915 Olentangy River Road, ENT, Suite 4000, Columbus |
From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.