Home › NCT05923606
Modulation of Brain Oscillations Underlying Working Memory
State-dependent Modulation of Interactions of Theta and Gamma Rhythms in Working Memory
Who can join
Ages 18 to 35 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Able to provide informed consent * Fluent in English. Exclusion Criteria: * History of a neurological/psychiatric disorder * Current use of psychotropic medications * Current use of substances and drugs that were shown to affect tES (transcranial electrical stimulation) efficacy (dopamine altering drugs, nicotine, NMDA (N-methyl-D-aspartate) antagonists/agonists, sodium/calcium channel blockers, norepinephrine reuptake inhibitors, GABAergic modulators and selective serotonin reuptake inhibitors) * Contraindications for tACS (e.g., history of seizures, metallic implants in the head or neck, implanted brain stimulators, vagus nerve stimulators, pacemakers, pregnancy)
About the study
This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie working memory. tACS is a noninvasive method used to modulate the timing and patterns of brain rhythms via weak electric currents passed through electrodes on the scalp.
What is being tested
- Active tACS (device)
- Placebo tACS (device)
Sponsor: Massachusetts General Hospital · Participants: 32 · Started: Jul 10, 2024
Contact the study team
- Allyson Smith, B.S. · Phone: (617) 726-1040
- Hamdi Eryilmaz, Ph.D. · Phone: (617) 643-7462
Official record on ClinicalTrials.gov — NCT05923606
Locations in the U.S.
| Massachusetts | Martinos Center for Biomedical Imaging, Charlestown |
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.