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MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial
MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial (METEOR-CRATR)
Who can join
Ages 18 and older · All sexes
Full eligibility criteria
Inclusion Criteria: * Confirmation of intent to receive radiotherapy for one of the following diagnoses: * Cervical cancer * Pancreatic cancer * ECOG performance status ≤ 2 * At least 18 years old * Able to understand and willing to sign an IRB-approved written informed consent document Exclusion Criteria: * Any issue (medical, anatomic, other) that might preclude safe acquisition of biospecimens at the discretion of the treating physician
About the study
This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-related data (imaging, dosimetry, clinical) before, during, and after treatment with definitive-intent chemoradiotherapy for patients with locally advanced cervical and pancreatic cancer.
What is being tested
- Tumor collection via biopsy (other)
- Blood collection (other)
- Diffusion basis spectrum imaging (DBSI) magnetic resonance imaging (MRI) (device)
Sponsor: Washington University School of Medicine · Participants: 60 · Started: Jan 11, 2024
Contact the study team
- Michael Waters, M.D., Ph.D. · Phone: 314-273-0275
Official record on ClinicalTrials.gov — NCT05975593
Locations in the U.S.
| Missouri | Washington University School of Medicine, St Louis |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.