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Deconstructing Post Stroke Hemiparesis

RecruitingObservational study

Deconstructing Post Stroke Hemiparesis for Precision Neurorehabilitation

Who can join

Ages 18 to 90 · All sexes

Full eligibility criteria
Inclusion Criteria:

* Diagnosis of a unilateral ischemic stroke occurring \>6 months prior as documented in medical chart
* Upper extremity motor impairment as measured by Fugl-Meyer Upper Extremity Assessment ≤60
* Ability to follow simple instructions in English

Exclusion Criteria:

* Greater than moderate difficulty using the arm and hand pre-dating the stroke as assessed by the questions adapted from the QuickDASH outcome measure score on any question \>= 3, which measures physical function and symptoms in people with difficulty using the arm and hand.
* Visual or auditory disorders resulting in the inability to see or hear, respectively, the stimuli presented as part of research sessions
* Inability to maintain a seated position for at least one hour
* Standard MRI exclusion (e.g., significant claustrophobia or inability to tolerate loud noises, cardiac pacemaker (unless MRI-safe), implanted device (deep brain stimulation) or metal in the brain, cervical spinal cord, or upper thoracic spinal cord)
* Standard (single-pulse) TMS exclusion which include (in addition to those listed for MRI) pregnancy/lactation/planning to become pregnant during the study, seizure disorder, and primary or secondary CNS tumors

About the study

TRACTs (DeconsTructing Post StRoke HemipAresis for PreCision NeurorehabiliTation) is a single timepoint study that aims to deconstruct post-stroke deficits of the upper extremity into distinct components and relate these components to brain anatomy and physiology.

Sponsor: Providence VA Medical Center · Participants: 75 · Started: Sep 5, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT05993221

Locations in the U.S.

Rhode IslandProvidence VA Medical Center, Providence

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.