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Frequent Standardized Oral Care Using Human Milk in the Neonatal Intensive Care Unit
Frequent Standardized Oral Care Using Human Milk to Prevent Oral Dysbiosis and Improve Health Outcomes in Premature Infants in the Neonatal Intensive Care Unit
Who can join
1 Hour – 3 Days · All sexes
Full eligibility criteria
Inclusion: * Mother ≥18 years of age * ≤ 30 weeks gestation * Born weighing ≤ 1500 grams Exclusion: * Congenital anomalies of the face, lungs, or gastrointestinal system * Not expected to live \> 7 days following delivery.
About the study
Premature infants are susceptible to complications related to infrequent and non-standardized oral care. Although the benefits of frequent standardized oral care are known to reduce oral dysbiosis (increased level of potentially pathogenic bacteria) and its associated complications in critically ill adults leading to established evidence-based guidelines, no such information exists for VLBW infants. The proposed study will prospectively follow 168 VLBW infants for 4 weeks following birth.
What is being tested
- Standardized oral Care (procedure)
Sponsor: University of Florida · Participants: 218 · Started: Nov 23, 2023
Contact the study team
- Leslie A Parker, PhD, APRN · Phone: 352-273-6384
Official record on ClinicalTrials.gov — NCT06000761
Locations in the U.S.
| Florida | Neonatal intensive care unit at Shands children's hospital at the Univeristy of Florida, Gainesville |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.