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Spatial-Motor Stroke-Rehab Study

RecruitingHealthy volunteers welcome

Novel Spatial-Motor Approaches to Improve Spatial Neglect and Walking Deficits Post-Stroke

Who can join

Ages 18 to 90 · All sexes · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

Young Adults Able Bodied (YAB) Individuals

* 18-30 years
* Able-Bodied (healthy without any physical disability or neurological disorder)

Older Adults Able-Bodied Individuals (OAB)

* 45-90 years
* Able-Bodied (healthy without any physical disability or neurological disorder)

Individuals with right hemisphere stroke (40-90 years)

* \>3 months following stroke.
* Presence of Aiming SN
* Ability to walk \>10m with or without assistive devices.
* Unilateral left-sided hemiparesis with gross arm strength of ≤ grade 4/5 on the Medical Research Council Scale
* Ability to follow 3-stage commands and provide informed consent.

Exclusion Criteria:

Young Adults Able-Bodied (YAB) Individuals and Older Adults Able-Bodied Individuals (OAB)

* History or evidence of orthopedic or physical disability
* History or evidence of neurological pathology
* Pregnancy (female)
* Uncontrolled hypertension
* Cardiac pacemaker or other implanted electronic system
* Presence of skin conditions preventing the electrical stimulation setup
* Impaired sensation in the left upper limb.
* Bruises or cuts at the stimulation electrode placement site
* Concurrent enrollment in rehabilitation or another investigational study.
* History or evidence of orthopedic or physical disability interfering with study procedures
* History or evidence of neurological pathology or disorder
* Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) that may interfere with study procedures
* Contraindications to TMS, such as metal implants, medications that can increase cortical excitability, and unexplained dizziness in the past 6 months

Individuals with right hemisphere stroke (40-90 years)

* History or brainstem strokes
* Cerebellar disorders
* Impaired sensation in the left upper limb.
* History of other neurological disorders
* Uncontrolled hypertension
* Cardiac pacemaker or other implanted electronic system
* Pregnancy (female)
* Presence of skin condition
* Bruises at the electrode placement site
* Severe uncontrolled medical problems (e.g., hypertension, cardiovascular disease, rheumatoid arthritis, active cancer or renal disease, epilepsy) or other medical conditions that can interfere with study procedures
* Contraindications to TMS, such as metal implants in the brain, medications that will increase cortical excitability, etc.

About the study

The purpose of this study is to understand how prism adaptation training with and without electrical stimulation changes visuospatial behavior, motor system neurophysiology, and walking dysfunction.

What is being tested

Sponsor: Emory University · Participants: 65 · Started: Apr 11, 2023

Contact the study team

Official record on ClinicalTrials.gov — NCT06053320

Locations in the U.S.

GeorgiaEmory Rehabilitation Hospital, Atlanta
Emory University Hospital (EUH), Atlanta
Executive Park, Atlanta

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.