Home › Gastroschisis › NCT06072976

The Influence of Feeding Source on the Gut Microbiome and Time to Full Feeds in Neonates With Congenital Gastrointestinal Pathologies

Who can join

0 Days – 55 Years · All sexes

Inclusion Criteria:

* Infants with gastroschisis, giant omphalocele, intestinal atresia, mid-gut volvulus, hirschsprungs disease.

Exclusion Criteria:

1. Infant has already been on feeds
2. Infants \<34 weeks gestation
3. Parents with contraindications to providing milk (i.e. drug use-cocaine, fentanyl, meth BUT oxy/suboxone/marijuana OK)
4. Complicated gastroschisis
5. Short gut syndrome
6. Additional congenital anomalies that affect ability to tolerate milk (i.e. cyanotic congenital heart disease BUT kidney disease ok)

About the study

This study explores the use of an exclusive human milk diet versus standard feeding practices to compare the influence on feeding outcomes and the gut bacteria in infants with intestinal differences.

What is being tested

• Standard of Care (dietary supplement)
• Exclusive Human Milk (dietary supplement)

Sponsor: Seattle Children's Hospital · Participants: 116 · Started: Jun 9, 2023

Contact the study team

• Leonel Arellano · Phone: 915-443-4390

Official record on ClinicalTrials.gov — NCT06072976

Locations in the U.S.

Conditions

• Gastroschisis

From ClinicalTrials.gov, data retrieved Oct 2, 2026. Each study sets its own eligibility; the study team decides who can join.