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Immersive Healing: The Therapeutic Potential of Virtual Reality

Immersive Healing: The Therapeutic Potential of Virtual Reality in Phantom Limb Experience

Who can join

Ages 18 and older · All sexes

Inclusion Criteria:

* History of major limb amputation
* Age \> 18 years old
* Presence of phantom limb pain or negative phantom sensation(s)

Exclusion Criteria:

* Active mental illness, neurological disease, or cognitive impairment that would interfere with survey completion
* Those without phantom limb pain or negative phantom limb sensations
* Non-English speaking

About the study

Phantom limb pain (PLP) is a significant and pervasive issue among upper limb amputees, severely impacting their quality of life. The literature delineating prevalence of upper versus lower limb amputations is limited, but the prevalence of total amputations in the United States is estimated to reach 3 million individuals by 2050, with approximately 185,000 new cases annually. PLP affects 60-68% of these patients, leading to heightened levels of anxiety, depression, and reduced overall well-being.

What is being tested

• virtual reality therapy (device)
• matched control group (other)

Sponsor: Wake Forest University Health Sciences · Participants: 20 · Started: Dec 21, 2023

Contact the study team

• Joshua Steinke · Phone: 704-942-4351

Official record on ClinicalTrials.gov — NCT06077227

Locations in the U.S.

Conditions

• Phantom Limb

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.