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Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

RecruitingPhase 2/3Healthy volunteers welcome

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS): a Prospective, Double-Blind, Randomized Controlled Trial

Who can join

Ages 18 and older · Women · Healthy volunteers welcome

Full eligibility criteria
Inclusion Criteria:

* Patients 18 years of age or older
* Female
* English Speaking
* Diagnosis of IC/PBS
* Have failed at least one prior treatment for IC/PBS

Exclusion Criteria:

* Patients less than 18 years of age
* Unable to provide consent
* Non-English speaking
* Patients with known anatomical malformations of the ureters, bladder, or urethra

About the study

Interstitial cystitis/painful bladder syndrome (IC/PBS) is a clinical syndrome in which patients report symptoms of bladder and/or pelvic pain with pressure and/ or discomfort associated with urinary frequency and urgency.

The primary objective of this study is to determine the efficacy of amniotic membrane therapy in patients with interstitial cystitis/painful bladder syndrome (IC/PBS) as defined by clinically-significant improvement in validated symptom questionnaires.

What is being tested

Sponsor: David Sheyn · Participants: 100 · Started: Jul 24, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06096597

Locations in the U.S.

OhioUniversity Hospitals, Clevleand

Conditions

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.