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Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury
A Novel Neurofeedback Intervention for Photosensitivity in Mild Traumatic Brain Injury
Who can join
Ages 18 to 65 · All sexes
Full eligibility criteria
Inclusion Criteria: * Ages 18-65 * Documented history of mTBI at least 6 months prior to initial study visit * Documented symptoms of photosensitivity * Eye exam within the last 12 months documenting best-corrected acuity of 20/20 or better, normal pupillary function, color vision, no abnormalities on OCT scan, and normal Humphrey Visual Field test Exclusion Criteria: * History of strabismus or amblyopia * Significant ocular media opacity that could reduce the amount of light entering the pupil in one or both eyes * Previous or current history of retinal or optic nerve pathology in one or both eyes * History of stroke and/or visual neglect * History of neurodegenerative disease (e.g., Parkinson's, multiple sclerosis) * History of epilepsy or seizures * History of motor tics * Current use of medications or substances that may severely affect pupillary response and/or increase photosensitivity * Individuals with impaired decision-making capacity * Illiterate or no English language proficiency
About the study
The goal of this study is to complete a pilot study testing the feasibility and acceptability of low-intensity pulse-based transcranial stimulation (LIP-tES) neurofeedback intervention for reducing photosensitivity symptoms in Veterans with a history of mild traumatic brain injury (mTBI). The study will also complete resting-state MRI scans to assess neurophysiological markers of photosensitivity and changes associated with LIP-tES intervention.
What is being tested
- Micro Current Neurofeedback Device using Low-Frequency Pulse-Based Transcranial Electrical Stimulation (device)
Sponsor: VA Office of Research and Development · Participants: 36 · Started: Jan 1, 2024
Contact the study team
- Francesca C Fortenbaugh, PhD · Phone: (857) 364-4362
Official record on ClinicalTrials.gov — NCT06109909
Locations in the U.S.
| Massachusetts | VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.