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Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)

Role of Senescent Cells in Uterine Fibroid Pathogenesis

Who can join

Ages 18 to 55 · Women

Inclusion Criteria:

* Subjects must be women above the age of ≥18 - ≤55 years.
* Women with suspected uterine fibroids.
* Subject must be or have been sexually active or have had a previous vaginal exam that used a speculum.
* Subject must be able to understand, read and speak English or Spanish and subsequently, be able to understand what she is consenting to in terms of procedures and use/disclosure of protected health information.

Exclusion Criteria:

* Unwilling to sign the consent form or complete questionnaire.
* Pregnancy.
* Cancer of the uterus

About the study

The investigators are evaluating the role of senescent cells in uterine fibroids.

Sponsor: Johns Hopkins University · Participants: 150 · Started: Nov 1, 2023

Contact the study team

• James Segars, MD · Phone: 410-614-2000
• Bhuchitra Singh, MD, MPH, MBA · Phone: 410-614-2000

Official record on ClinicalTrials.gov — NCT06135870

Locations in the U.S.

Conditions

• Uterine Fibroids

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.