Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation
RecruitingPhase 2Healthy volunteers welcome
Changes in Rate of Hemorrhage With Prophylactic Oxytocin for Second Trimester Dilation and Evacuation in the Clinic Setting
Who can join
Ages 18 to 55 · Women · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * clinic-based D\&E at 18 weeks gestational age and above * speaks English or Spanish Exclusion Criteria: * refuses IV * history of coagulopathy * anticoagulant use in the preceding five days * chorioamnionitis or sepsis * suspected placenta accreta spectrum * intrauterine fetal demise * multiple gestation * use of misoprostol for cervical preparation
About the study
The purpose of this study is to assess the effectiveness of prophylactic oxytocin on hemorrhage rates for second trimester dilation and evacuation (D\&E) in the clinic setting.
What is being tested
- Oxytocin + normal saline (drug)
- Normal saline (drug)
Sponsor: University of Colorado, Denver · Participants: 150 · Started: May 2, 2024
Contact the study team
- Megan Masten, MD · Phone: 303-724-8576
Official record on ClinicalTrials.gov — NCT06141447
Locations in the U.S.
| Colorado | Comprehensive Women's Health Center, Denver |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.