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Heme and Non-heme Iron Intakes, Gut Microbiota, and Influence on Host Iron Absorption
RecruitingObservational studyHealthy volunteers welcome
Who can join
Ages 18 to 40 · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Healthy adults * Age between 18- 40y * Non-smoking * Not currently taking vitamin, mineral, prebiotic, and probiotic supplements. * Females: premenopausal and not pregnant or lactating * No preexisting medical complications (such as eating disorders, hemoglobinopathies, malabsorption diseases, steroid use, substance abuse history, or taking medications known to influence iron homeostasis) * Body mass index (BMI) between 18 - 27 kg/m2. Exclusion Criteria: * BMI \<18 or \> 27 kg/m2, * Age \<18 y or \> 40y, * Smoking * Pregnancy, lactating * Have gastrointestinal disorders/malabsorption diseases/hemoglobinopathies/dietary restrictions/steroid use/ medication use of medications known to impact iron status, iron utilization or inflammatory status * Currently take vitamin, mineral, prebiotic, and probiotic supplements. * Recently received antibiotic treatment
About the study
The FeMicrobiome study will evaluate gut microbiome features and their relationships with dietary iron absorption in healthy adults. The investigators hypothesize that (1) the gut microbiota can be shaped by the heme and non-heme Fe content of the diet and that (2) this will influence individual variation in dietary Fe absorption.
Sponsor: Cornell University · Participants: 120 · Started: Jan 15, 2023
Contact the study team
- Kimberly O O'Brien, PhD · Phone: 607-255-3743
Official record on ClinicalTrials.gov — NCT06146608
Locations in the U.S.
| New York | Cornell University, Ithaca |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.