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Caries Detection With Two Different Caries Detecting Devices
A Pilot Clinical Trial Comparing the Efficacy of Caries Detection With a Novel Caries Detecting Rinse and Existing Diagnostic Tools
Who can join
Ages 21 and older · All sexes · Healthy volunteers welcome
Full eligibility criteria
Inclusion Criteria: * Patients of TUSDM Comprehensive Care Clinic * Adult patients over the age of 21 * Extreme/High Caries Risk classification per TUSDM Caries Management by Risk Assessment (CAMBRA) form * Presence of 2 or more initial active primary carious lesions on a free coronal surface of any tooth by visual assessment, QLF, and LumiCare™ * Presence of at least 1 cavitated lesion * Updated (no more than 6 months old) bite wing radiographs available. * Patients who responded either yes/no to use of e-cigarettes/vapes * 1 active caries, 1 inactive caries and 1 sound tooth surface. Exclusion Criteria: * Low or moderate caries risk classification per TUSDM CAMBRA form * No clinically detectable carious lesions on free coronal surfaces * No cavitated caries lesions * Carious teeth with caries lesions concomitant with extrinsic stains, fluorosis, or developmental defects. * Patients who responded yes to the use of conventional cigarettes or smokeless tobacco
About the study
The primary aim of this study will be to compare the effectiveness of the novel LumiCare™ rinse and with QLF in determining caries progression. The secondary aim is to compare the progression of carious lesions between patients who reported use of e-cigarettes/vapes and those who did not.
What is being tested
- LumiCare rinse (device)
- QLF Inspektor Pro Imaging (device)
Sponsor: Tufts University · Participants: 60 · Started: Apr 1, 2025
Contact the study team
- Karina Irusa, BDS,MS · Phone: 6176362408
- Ann-Marie Billig · Phone: 6176363931
Official record on ClinicalTrials.gov — NCT06152081
Locations in the U.S.
| Massachusetts | Tufts University School of Dental Medicine, Boston |
Conditions
From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.