Powered Prosthesis for Use With TF Osseointegration Recipients

Inclusion Criteria:

* Unilateral lower limb amputation at the transfemoral level
* Existing prosthesis wearer
* K2/K3/K4 level ambulation
* 18-70 years old
* Mini-Mental State Exam (MMSE) score greater than 17
* Ability to demonstrate proper safety with passive prosthesis
* Candidate for a myoelectric prosthesis (can generate mV level electromyographic EMG signals as detected by surface electrodes
* Candidate for OI surgery as verified by surgical team or has previously received OI
* Candidate for TMR surgery as verified by surgical team or has previously received TMR

Exclusion Criteria:

* Unable to successfully receive osseointegration and TMR
* Significant new injury that would prevent use of a prosthesis: Ability to consistently wear prosthesis and perform activities of daily living and specific performance tasks is necessary to properly evaluate the relative benefits of the intervention
* Cognitive impairment sufficient to adversely affect understanding of or compliance with study requirements, ability to communicate experiences, or ability to give informed consent: The ability to understand and comply with requirements of the study is essential in order for the study to generate useable, reliable data.
* Visually impaired
* Proximal nerve injury that prevents TMR
* Individuals who smoke: may interfere with OI process from both bone healing and soft tissue standpoints
* Individuals with active implants.
* Significant comorbidity that would preclude completion of the study, use of prostheses, or would otherwise prevent data acquisition by researchers