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Effects of Processed Foods on Brain Reward Circuitry and Food Cue Learning

RecruitingObservational study

Who can join

Ages 13 to 15 · All sexes

Full eligibility criteria
Inclusion Criteria:

* female and male adolescents 13-15 years of age
* age- and sex- adjusted zBMI scores between the 25th and 75th percentile
* participant and their guardian must be able to read and speak English to gather valid consent

Exclusion Criteria:

* current eating disorders or other major psychiatric disorders (e.g., depression, bipolar, schizophrenia, substance use disorder)
* fMRI contra-indicators (e.g., metal implants, braces, claustrophobia, pregnancy)
* serious medical problems (e.g., Type 2 diabetes, cancer)
* history of food allergies or restrictive dietary requirements (e.g., lactose intolerance, vegan)
* use of psychoactive drugs more than once weekly
* medications that impact appetite or reward functioning (e.g., metformin, anti-psychotic medication, insulin)

About the study

Examine if ultra-processed (UP) foods are more effective in activating reward, attention, and memory brain regions and in promoting food cue learning than minimally-processed foods. Assess individual differences in neurobehavioral responses to UP foods.

Sponsor: Stanford University · Participants: 162 · Started: Oct 4, 2024

Contact the study team

Official record on ClinicalTrials.gov — NCT06165952

Locations in the U.S.

CaliforniaStanford University, Stanford

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.